黄叶飞,男,汉族,中共党员,江苏溧阳人,医学博士,副教授。博士毕业于南京医科大学公共卫生学院劳动卫生与环境卫生学专业。徐州医科大学2015年“优秀人才计划”引进博士,目前就职于公共卫生学院劳动与环境卫生学教研室,担任教研室副主任。
联系方式:E-mail:huangyefei@xzhmu.edu.cn。
学术兼职:中国毒理学会会员、中国环境诱变剂学会会员、第五届江苏省预防医学会卫生毒理与风险评估专业委员会青年委员、江苏省毒理学会第二届管理毒理与风险评估专业委员会委员。
主要研究方向:1、植物化学物的抗炎、抗肿瘤作用及机制研究;2、环境污染物暴露致肿瘤发生发展的作用机制研究。
主要科研成果:主持或参与国家级及省部级等课题10余项,其中主持国家自然科学基金青年项目(81703207,20万)1项、国家博士后基金面上项目(2017M611915,5万)1项、江苏省博士后基金面上项目(1601046B,4万)1项、江苏省高校自然科学基金面上项目(16KJD330002,1万)1项、徐州医科大学优秀人才科研启动基金(D2016025,30万)1项,在Journal of Hazardous Materials、Ecotoxicology And Environmental Safety、Food & Function、Cell Death & Disease、Journal of Gastroenterology、Scientific Reports、Anti-Cancer Drugs等国内外高水平杂志发表SCI论文多篇。
代表性论著(*通讯作者):
1.Min Jiang, Jingyi Han, Qun Ma, Xue Chen, Renjie Xu, Qing Wang, Jia Zheng, Weimin Wang, Jun Song,Yefei Huang*, Yansu Chen*; Nicotine-derived NNK promotes CRC progression through activating TMUB1/AKT pathway in METTL14/YTHDF2-mediated m6A manner. Journal of Hazardous Materials, 2024, 467: 133692.(中科院一区)
2. Qing Wang,Yefei Huang, Min Jiang, Yu Tang, Qinzhi Wang, Longlong Bai, Chenglong Yu, Xinyue Yang, Kun Ding, Weimin Wang*, Jin Bai*, Yansu Chen*; The demethylase ALKBH5 mediates ZKSCAN3 expression through the m6A modification to activate VEGFA transcription and thus participates in MNNG-induced gastric cancer progression. Journal of Hazardous Materials, 2024, 473: 134690.(中科院一区)
3.Lingling Li, Min Jiang, Weimin Wang, Xingyue Cao, Qun Ma, Jingyi Han, Zixuan Liu,Yefei Huang*, Yansu Chen*; DNA demethylase TET2-mediated reduction of HADHB expression contributes to cadmium-induced malignant progression of colorectal cancer. Ecotoxicology and Environmental Safety, 2024, 280: 116579. SCIE.(中科院一区)
4.Yefei Huang; Zixuan Liu; Lingling Li; Min Jiang; Yu Tang; Li Zhou; Jing Li; Yansu Chen; Sesamin inhibits hypoxia-stimulated angiogenesis via the NF-κB p65/HIF-1α/VEGFA signaling pathway in human colorectal cancer. Food & Function, 2022, 13(17): 8989-8997.SCIE.(中科院一区)
5.Yefei Huang; Qinzhi Wang; Yu Tang; Zixuan Liu; Guixiang Sun; Zhaojun Lu; Yansu Chen; Identification and validation of a cigarette smoke-related five-gene signature as a prognostic biomarker in kidney renal clear cell carcinoma. Scientific Reports, 2022, 12(1): 2189. SCIE.(中科院二区)
6. Xuxu Wang; Jiahao Qiao; Chaoyi Zou; Yutao Zhao;Yefei Huang*; Sesamin induces cell cycle arrest and apoptosis through p38/C-Jun N-terminal kinase mitogen-activated protein kinase pathways in human colorectal cancer cells. Anti-Cancer Drugs, 2021, 32(3): 248-256. SCIE.(中科院四区)
7.Yefei Huang; Zhe Zhang; Meng Zhang; Yansu Chen; Jun Song; Pingfu Hou; Hongmei Yong; Junnian Zheng; Jin Bai; CUL1 promotes breast cancer metastasis through regulating EZH2-induced the autocrine expression of the cytokines CXCL8 and IL11. Cell Death & Disease, 2018, 10(1): 2. SCIE.(中科院一区)
8.Yefei Huang; Weimin Wang; Yansu Chen; Yulin Huang; Jianbing Zhang; Song He; Yongfei Tan; Fulin Qiang; Aiping Li; Oluf Dimitri Roe; Shouyu Wang; Yan Zhou; Jianwei Zhou; The opposite prognostic significance of nuclear and cytoplasmic p21 expression in resectable gastric cancer patients. Journal of Gastroenterology, 2014, 49(11): 1441-1452. SCIE.(中科院二区)
9.孙晶晶,季影,王勉,牟明军,邹璟,黄叶飞*.可可粉对DSS诱导的小鼠结肠炎的抑制作用及分子机制,现代食品科技, 2022, 38(5): 16-23.北大核心.
10.刘紫瑄,李玲玲,黄叶飞*.新橙皮苷对葡聚糖硫酸钠致小鼠溃疡性结肠炎的保护作用及其机制.现代预防医学, 2022, 49(24): 4505-4512.北大核心.
获奖情况:
1.第十届“全国大学生基础医学创新研究暨实验设计论坛”预防医学赛道国家级优秀奖、省级三等奖、校级一等奖、国际赛道校级优秀奖,2024,指导教师。
2.第九届全国大学生生命科学竞赛(科学探究类)江苏赛区三等奖,2024,指导教师。
3.第十届全国大学生医学技术技能大赛预防医学专业赛道华东赛区三等奖,2021,指导教师。